Inhibition of CD44 Gene Expression in Human Skin Models, Using Self-Delivery Short Interfering RNA Administered by Dissolvable Microneedle Arrays

Treatment of skin disorders with short interfering RNA (siRNA)-based therapeutics requires the development of effective delivery methodologies that reach target cells in affected tissues. Successful delivery of functional siRNA to the epidermis requires (1) crossing the stratum corneum, (2) transfer...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lara, Maria Fernanda, González-González, Emilio, Speaker, Tycho J., Hickerson, Robyn P., Leake, Devin, Milstone, Leonard M., Contag, Christopher H., Kaspar, Roger L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2012
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413896/
https://ncbi.nlm.nih.gov/pubmed/22480249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.211
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