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Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer
The transcription factor (TF) SOX2 is essential for the maintenance of pluripotency and self-renewal in embryonic stem cells. In addition to its normal stem cell function, SOX2 over-expression is associated with cancer development. The ability to selectively target this and other oncogenic TFs in ce...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413152/ https://ncbi.nlm.nih.gov/pubmed/22561374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks360 |
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