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Epigenetic reprogramming of cancer cells via targeted DNA methylation

An obstacle in the treatment of human diseases such as cancer is the inability to selectively and effectively target historically undruggable targets such as transcription factors. Here, we employ a novel technology using artificial transcription factors (ATFs) to epigenetically target gene expressi...

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Bibliografski detalji
Glavni autori: Rivenbark, Ashley G., Stolzenburg, Sabine, Beltran, Adriana S., Yuan, Xinni, Rots, Marianne G., Strahl, Brian D., Blancafort, Pilar
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368819/
https://ncbi.nlm.nih.gov/pubmed/22419067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.19507
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