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Epigenetic reprogramming of cancer cells via targeted DNA methylation
An obstacle in the treatment of human diseases such as cancer is the inability to selectively and effectively target historically undruggable targets such as transcription factors. Here, we employ a novel technology using artificial transcription factors (ATFs) to epigenetically target gene expressi...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368819/ https://ncbi.nlm.nih.gov/pubmed/22419067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.19507 |
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