Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

The transcription factor (TF) SOX2 is essential for the maintenance of pluripotency and self-renewal in embryonic stem cells. In addition to its normal stem cell function, SOX2 over-expression is associated with cancer development. The ability to selectively target this and other oncogenic TFs in ce...

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Autori principali: Stolzenburg, Sabine, Rots, Marianne G., Beltran, Adriana S., Rivenbark, Ashley G., Yuan, Xinni, Qian, Haili, Strahl, Brian D., Blancafort, Pilar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413152/
https://ncbi.nlm.nih.gov/pubmed/22561374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks360
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