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Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation
Ionizing radiation (IR) produces direct two-ended DNA double-strand breaks (DSBs) primarily repaired by non-homologous end joining (NHEJ). It is, however, well established that homologous recombination (HR) is induced and required for repair of a subset of DSBs formed following IR. Here, we find tha...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413124/ https://ncbi.nlm.nih.gov/pubmed/22505579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks315 |
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