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Dose Dependent Effect of Anti-CTLA-4 on Survival in Sepsis
BACKGROUND: Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) is one of the critical inhibitory regulators of early stages of T cell activation and proliferation which opposes the actions of CD28-mediated co-stimulation. Anti-CTLA-4 therapy has been effective clinically in enhancing immunity and improving s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412306/ https://ncbi.nlm.nih.gov/pubmed/21368717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3182168cce |
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