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Delayed administration of anti‐PD‐1 antibody reverses immune dysfunction and improves survival during sepsis

There is increasing recognition that a major pathophysiologic event in sepsis is the progression to an immunosuppressive state in which the host is unable to eradicate invading pathogens. Although there are likely numerous causes for the immunosuppression, expression of negative costimulatory molecu...

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Detaylı Bibliyografya
Yayımlandı:J Leukoc Biol
Asıl Yazarlar: Brahmamdam, Pavan, Inoue, Shigeaki, Unsinger, Jacqueline, Chang, Katherine C., McDunn, Jonathan E., Hotchkiss, Richard S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607999/
https://ncbi.nlm.nih.gov/pubmed/20483923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0110037
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