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Anti-Programed Cell Death Ligand 1 Peptide Improves Survival in Sepsis

BACKGROUND: Sepsis remains a leading cause of death in most ICUs. Many deaths in sepsis are due to nosocomial infections in patients who have entered the immunosuppressive phase of the disorder. One cause of immunosuppression in sepsis is T-cell exhaustion mediated by programmed cell death-1 (PD-1)...

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Detalhes bibliográficos
Publicado no:J Surg Res
Main Authors: Shindo, Yuichiro, McDonough, Jacquelyn S., Chang, Katherine C., Ramachandra, Murali, Sasikumar, Pottayil G., Hotchkiss, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535083/
https://ncbi.nlm.nih.gov/pubmed/27993215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2016.08.099
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