Surrogate endpoints for overall survival in anti-programmed death-1 and anti-programmed death ligand 1 trials of advanced melanoma

BACKGROUND: We assessed the surrogacy of objective response rate (ORR), disease control rate (DCR) and progression-free survival (PFS) for overall survival (OS) in anti-PD-1/PD-L1 trials of metastatic melanoma through a meta-analysis of randomized controlled trials (RCTs). METHODS: PubMed and EMBASE...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Ther Adv Med Oncol
Autori principali: Nie, Run-Cong, Yuan, Shu-Qiang, Wang, Yun, Zou, Xue-Bin, Chen, Shi, Li, Shu-Man, Duan, Jin-Ling, Zhou, Jie, Chen, Guo-Ming, Luo, Tian-Qi, Zhou, Zhi-Wei, Li, Yuan-Fang
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2020
Soggetti:
Meta-Analysis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301660/
https://ncbi.nlm.nih.gov/pubmed/32595775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835920929583
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