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Review of meta-analyses evaluating surrogate endpoints for overall survival in oncology

Overall survival (OS) is the gold standard in measuring the treatment effect of new drug therapies for cancer. However, practical factors may preclude the collection of unconfounded OS data, and surrogate endpoints are often used instead. Meta-analyses have been widely used for the validation of sur...

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Detalhes bibliográficos
Main Authors: Sherrill, Beth, Kaye, James A, Sandin, Rickard, Cappelleri, Joseph C, Chen, Connie
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481854/
https://ncbi.nlm.nih.gov/pubmed/23109809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S36683
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