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Surrogate endpoints for overall survival in randomised controlled trials of localised osteosarcoma: A meta-analytic evaluation

Event-free survival (EFS) is considered the most reliable surrogate endpoint for overall survival (OS) in randomised controlled trials (RCTs) of adjuvant therapies for malignant tumours. However, the surrogacy of intermediate endpoints such as EFS for OS in trials of patients with osteosarcoma has n...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Tanaka, Kazuhiro, Kawano, Masanori, Iwasaki, Tatsuya, Matsuda, Shogo, Itonaga, Ichiro, Tsumura, Hiroshi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244479/
https://ncbi.nlm.nih.gov/pubmed/32444660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65591-z
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