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Anti-Programed Cell Death Ligand 1 Peptide Improves Survival in Sepsis

BACKGROUND: Sepsis remains a leading cause of death in most ICUs. Many deaths in sepsis are due to nosocomial infections in patients who have entered the immunosuppressive phase of the disorder. One cause of immunosuppression in sepsis is T-cell exhaustion mediated by programmed cell death-1 (PD-1)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Surg Res
Main Authors: Shindo, Yuichiro, McDonough, Jacquelyn S., Chang, Katherine C., Ramachandra, Murali, Sasikumar, Pottayil G., Hotchkiss, Richard S.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535083/
https://ncbi.nlm.nih.gov/pubmed/27993215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2016.08.099
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