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OX40 Agonistic Antibody Reverses Immune Suppression and Improves Survival in Sepsis

A defining feature of protracted sepsis is development of immunosuppression that is thought to be a major driving force in the morbidity and mortality associated with the syndrome. The immunosuppression that occurs in sepsis is characterized by profound apoptosis-induced depletion of CD4 and CD8 T c...

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Библиографические подробности
Опубликовано в: :J Leukoc Biol
Главные авторы: Unsinger, Jacqueline, Walton, Andrew H., Blood, Tessa, Tenney, Daniel, Quigley, Michael, Drewry, Anne M., Hotchkiss, Richard S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887130/
https://ncbi.nlm.nih.gov/pubmed/33264454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.5HI0720-043R
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