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OX40 Agonistic Antibody Reverses Immune Suppression and Improves Survival in Sepsis

A defining feature of protracted sepsis is development of immunosuppression that is thought to be a major driving force in the morbidity and mortality associated with the syndrome. The immunosuppression that occurs in sepsis is characterized by profound apoptosis-induced depletion of CD4 and CD8 T c...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Unsinger, Jacqueline, Walton, Andrew H., Blood, Tessa, Tenney, Daniel, Quigley, Michael, Drewry, Anne M., Hotchkiss, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887130/
https://ncbi.nlm.nih.gov/pubmed/33264454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.5HI0720-043R
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