Localization and quaternary structure of the PKA RIβ holoenzyme

Specificity for signaling by cAMP-dependent protein kinase (PKA) is achieved by both targeting and isoform diversity. The inactive PKA holoenzyme has two catalytic (C) subunits and a regulatory (R) subunit dimer (R(2):C(2)). Although the RIα, RIIα, and RIIβ isoforms are well studied, little is known...

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Detalhes bibliográficos
Main Authors: Ilouz, Ronit, Bubis, José, Wu, Jian, Yim, Yun Young, Deal, Michael S., Kornev, Alexandr P., Ma, Yuliang, Blumenthal, Donald K., Taylor, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411989/
https://ncbi.nlm.nih.gov/pubmed/22797896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209538109
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