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Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C

The anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase is tightly regulated to ensure programmed proteolysis in cells. The activity of the APC/C is positively controlled by cyclin-dependent kinase (CDK), but a second level of control must also exist because phosphorylation inactivates Cdc...

詳細記述

保存先:
書誌詳細
主要な著者: Labit, Helene, Fujimitsu, Kazuyuki, Bayin, N Sumru, Takaki, Tohru, Gannon, Julian, Yamano, Hiroyuki
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411074/
https://ncbi.nlm.nih.gov/pubmed/22713866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.168
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