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PP2A‐B56 binds to Apc1 and promotes Cdc20 association with the APC/C ubiquitin ligase in mitosis

Cell cycle progression and genome stability are regulated by a ubiquitin ligase, the anaphase‐promoting complex/cyclosome (APC/C). Cyclin‐dependent kinase 1 (Cdk1) has long been implicated in APC/C activation; however, the molecular mechanisms of governing this process in vivo are largely unknown. R...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Fujimitsu, Kazuyuki, Yamano, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945068/
https://ncbi.nlm.nih.gov/pubmed/31825153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948503
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