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Proteolytic Degradation of the Yap1 Transcription Factor Is Regulated by Subcellular Localization and the E3 Ubiquitin Ligase Not4

Saccharomyces cerevisiae Yap1 is a transcriptional regulatory protein that serves as a central determinant of oxidative stress tolerance. Activity of this factor is regulated in large part by control of its subcellular location. In the absence of oxidants, Yap1 is primarily located in the cytoplasm....

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Bibliografski detalji
Glavni autori: Gulshan, Kailash, Thommandru, Bernice, Moye-Rowley, W. Scott
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411017/
https://ncbi.nlm.nih.gov/pubmed/22707721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.384719
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