Activation of neocarzinostatin chromophore and formation of nascent DNA damage do not require molecular oxygen.
Thiol-activated neocarzinostatin chromophore abstracts tritium from the 5', but not from the 1' or 2' positions of deoxyribose in DNA and incorporates it into a stable, non-exchangeable form. The abstracted tritium remains covalently associated with the chromophore or its degradation product after t...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1985
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341101/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3158880/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.5.1637 |
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