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Hematopoietic stem cell development requires transient Wnt/β-catenin activity

Understanding how hematopoietic stem cells (HSCs) are generated and the signals that control this process is a crucial issue for regenerative medicine applications that require in vitro production of HSC. HSCs emerge during embryonic life from an endothelial-like cell population that resides in the...

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Détails bibliographiques
Auteurs principaux: Ruiz-Herguido, Cristina, Guiu, Jordi, D'Altri, Teresa, Inglés-Esteve, Julia, Dzierzak, Elaine, Espinosa, Lluis, Bigas, Anna
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409499/
https://ncbi.nlm.nih.gov/pubmed/22802352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120225
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