Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1

Specific deletion of Notch1 and RBPjκ in the mouse results in abrogation of definitive haematopoiesis concomitant with the loss of arterial identity at embryonic stage. As prior arterial determination is likely to be required for the generation of embryonic haematopoiesis, it is difficult to establi...

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Autores principales: Robert-Moreno, Àlex, Guiu, Jordi, Ruiz-Herguido, Cristina, López, M Eugenia, Inglés-Esteve, Julia, Riera, Lluis, Tipping, Alex, Enver, Tariq, Dzierzak, Elaine, Gridley, Thomas, Espinosa, Lluis, Bigas, Anna
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486417/
https://ncbi.nlm.nih.gov/pubmed/18528438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.113
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