CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy

Triple-negative breast cancer (TNBC) is an aggressive disease that lacks established markers to direct therapeutic intervention. Thus, these tumors are routinely treated with cytotoxic chemotherapies (e.g., anthracyclines), which can cause severe side effects that impact quality of life. Recent stud...

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Bibliografiske detaljer
Main Authors: McClendon, A. Kathleen, Dean, Jeffry L., Rivadeneira, Dayana B., Yu, Justine E., Reed, Christopher A., Gao, Erhe, Farber, John L., Force, Thomas, Koch, Walter J., Knudsen, Erik S.
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409014/
https://ncbi.nlm.nih.gov/pubmed/22751436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21127
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