TMPRSS2- Driven ERG Expression In Vivo Increases Self-Renewal and Maintains Expression in a Castration Resistant Subpopulation

Genomic rearrangements commonly occur in many types of cancers and often initiate or alter the progression of disease. Here we describe an in vivo mouse model that recapitulates the most frequent rearrangement in prostate cancer, the fusion of the promoter region of TMPRSS2 with the coding region of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Casey, Orla M., Fang, Lei, Hynes, Paul G., Abou-Kheir, Wassim G., Martin, Philip L., Tillman, Heather S., Petrovics, Gyorgy, Awwad, Hibah O., Ward, Yvona, Lake, Ross, Zhang, Luhua, Kelly, Kathleen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408501/
https://ncbi.nlm.nih.gov/pubmed/22860005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041668
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