Quantitative Expression of TMPRSS2 Transcript in Prostate Tumor Cells Reflects TMPRSS2-ERG Fusion Status

TMPRSS2-ERG fusion is the most common oncogenic rearrangement in prostate cancer (CaP). Due to this chromosomal rearrangement one TMPRSS2 allele loses its promoter, and one of the ERG alleles gains that promoter leading to its overexpression in these tumor cells. Some studies suggest that TMPRSS2, a...

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Detalhes bibliográficos
Main Authors: Mwamukonda, Kuwong, Chen, Yongmei, Ravindranath, Lakshmi, Furusato, Bungo, Hu, Ying, Sterbis, Joseph, Osborn, David, Rosner, Inger, Sesterhenn, Isabell A., McLeod, David G., Srivastava, Shiv, Petrovics, Gyorgy
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820150/
https://ncbi.nlm.nih.gov/pubmed/19597533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pcan.2009.28
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