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Imaging of Lytic Granule Exocytosis in CD8(+) Cytotoxic T Lymphocytes Reveals a Modified Form of Full Fusion

Here we imaged the exocytosis of lytic granules from human CD8(+) cytotoxic T lymphocytes using rapid Total Internal Refection microscopy, Lamp-1 tagged with mGFP to follow the fate of the lytic granule membrane, and granzyme A, granzyme B or serglycin tagged with mRFP to follow the fate of lytic gr...

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Autors principals: Martina, Jose A., Wu, Xufeng S., Catalfamo, Marta, Sakamoto, Takeshi, Yi, Chang, Hammer, John A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407469/
https://ncbi.nlm.nih.gov/pubmed/21843881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2011.07.004
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