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Syntaxin 4 mediates endosome recycling for lytic granule exocytosis in cytotoxic T-lymphocytes

Adaptive and innate immunity utilize the perforin-killing pathway to eliminate virus-infected or cancer cells. Cytotoxic T-lymphocytes (CTLs) and Natural Killer cells mediate this process by releasing toxic proteins at the contact area with target cells known as immunological synapse (IS). Formation...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Spessott, Waldo A., Sanmillan, Maria L., Kulkarni, Vineet V., McCormick, Margaret E., Giraudo, Claudio G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513838/
https://ncbi.nlm.nih.gov/pubmed/28471021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12490
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