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Imaging of Lytic Granule Exocytosis in CD8(+) Cytotoxic T Lymphocytes Reveals a Modified Form of Full Fusion
Here we imaged the exocytosis of lytic granules from human CD8(+) cytotoxic T lymphocytes using rapid Total Internal Refection microscopy, Lamp-1 tagged with mGFP to follow the fate of the lytic granule membrane, and granzyme A, granzyme B or serglycin tagged with mRFP to follow the fate of lytic gr...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407469/ https://ncbi.nlm.nih.gov/pubmed/21843881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2011.07.004 |
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