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Viral Reverse Transcriptases Show Selective High Affinity Binding to DNA-DNA Primer-Templates that Resemble the Polypurine Tract

Previous results using a SELEX (Systematic Evolution of Ligands by Exponential Enrichment)-based approach that selected DNA primer-template duplexes binding with high affinity to HIV reverse transcriptase (RT) showed that primers mimicking the 3′ end, and in particular the six nt terminal G tract, o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nair, Gauri R., Dash, Chandravanu, Le Grice, Stuart F. J., DeStefano, Jeffrey J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407194/
https://ncbi.nlm.nih.gov/pubmed/22848574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041712
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