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Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase
HIV-1 reverse transcriptase (RT) possesses both DNA polymerase activity and RNase H activity that act in concert to convert single-stranded RNA of the viral genome to double-stranded DNA that is then integrated into the DNA of the infected cell. Reverse transcriptase–catalyzed reverse transcription...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766924/ https://ncbi.nlm.nih.gov/pubmed/29122886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.798256 |
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