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Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3′ polypurine tract

Recent structural analyses indicate that localized regions of abnormal base pairing exist within RNA/DNA hybrids containing the HIV-1 polypurine tract (PPT) and that these distortions may play a role in PPT function. To examine this directly, we have introduced pyrrolo-deoxycytosine (pdC), a fluores...

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Autors principals: Dash, Chandravanu, Rausch, Jason W., Le Grice, Stuart F. J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC390295/
https://ncbi.nlm.nih.gov/pubmed/15004241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh307
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