Structural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligands

The interactions of archetypical nucleic acid ligands with the HIV-1 polypurine tract (PPT) RNA:DNA hybrid, as well as analogous DNA:DNA, RNA:RNA and swapped hybrid substrates, were used to probe structural features of the PPT that contribute to its specific recognition and processing by reverse tra...

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Detalhes bibliográficos
Main Authors: Turner, Kevin B., Brinson, Robert G., Yi-Brunozzi, Hye Young, Rausch, Jason W., Miller, Jennifer T., Le Grice, Stuart F.J., Marino, John P., Fabris, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377446/
https://ncbi.nlm.nih.gov/pubmed/18400780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn129
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