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CD8(+) T Cells from Mice Transnuclear for a TCR that Recognizes a Single H-2K(b)-Restricted MHV68 Epitope Derived from gB-ORF8 Help Control Infection
To study the CD8(+) T cell response against a mouse γ-herpes virus, we generated K(b)-MHV-68-ORF8(604–612) RAG(−/−) CD8(+) T cell receptor transnuclear (TN) mice as a source of virus-specific CD8(+) T cells. K(b)-ORF8-Tet(+) CD8(+) T cells, expanded in the course of a resolving MHV-68 infection, ser...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406328/ https://ncbi.nlm.nih.gov/pubmed/22832272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.03.009 |
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