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A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation
Antigen presenting cells (APCs) that express a catalytically inactive version of the deubiquitylase YOD1 (YOD1-C160S) present exogenous antigens more efficiently to CD8(+) T cells, both in vitro and in vivo. Compared with controls, immunization of YOD1-C160S mice led to greater expansion of specific...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575758/ https://ncbi.nlm.nih.gov/pubmed/23243279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-447409 |
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