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Interleukin-6: A bone marrow stromal cell paracrine signal that induces neuroendocrine differentiation and modulates autophagy in bone metastatic PCa cells

Autophagy reallocates nutrients and clears normal cells of damaged proteins and organelles. In the context of metastatic disease, invading cancer cells hijack autophagic processes to survive and adapt in the host microenvironment. We sought to understand how autophagy is regulated in the metastatic...

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Autors principals: Delk, Nikki A., Farach-Carson, Mary C.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405839/
https://ncbi.nlm.nih.gov/pubmed/22441019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19226
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