p62/SQSTM1 is required for cell survival of apoptosis-resistant bone metastatic prostate cancer cell lines

BACKGROUND: Bone marrow stromal cell (BMSC) paracrine factor(s) can induce apoptosis in bone metastatic prostate cancer (PCa) cell lines. However, the PCa cells that escape BMSC-induced apoptosis can upregulate cytoprotective autophagy. METHODS: C4-2, C4-2B, MDA PCa 2a, MDA PCa 2b, VCaP, PC3, or DU1...

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Bibliografiske detaljer
Main Authors: Chang, Megan A., Morgado, Micaela, Warren, Curtis R., Hinton, Cimona V., Farach-Carson, Mary C., Delk, Nikki A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877418/
https://ncbi.nlm.nih.gov/pubmed/24122957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22737
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