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Interleukin-6: A bone marrow stromal cell paracrine signal that induces neuroendocrine differentiation and modulates autophagy in bone metastatic PCa cells

Autophagy reallocates nutrients and clears normal cells of damaged proteins and organelles. In the context of metastatic disease, invading cancer cells hijack autophagic processes to survive and adapt in the host microenvironment. We sought to understand how autophagy is regulated in the metastatic...

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Главные авторы: Delk, Nikki A., Farach-Carson, Mary C.
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405839/
https://ncbi.nlm.nih.gov/pubmed/22441019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19226
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