Autocrine and Paracrine Interactions between Multiple Myeloma Cells and Bone Marrow Stromal Cells by Growth Arrest-specific Gene 6 Cross-talk with Interleukin-6

The pathogenesis of multiple myeloma (MM) has not yet been fully elucidated. Our microarray analysis and immunohistochemistry revealed significant up-regulation of growth arrest-specific gene 6 (Gas6), a vitamin K-dependent protein with a structural homology with protein S, in bone marrow (BM) cells...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Furukawa, Miki, Ohkawara, Hiroshi, Ogawa, Kazuei, Ikeda, Kazuhiko, Ueda, Koki, Shichishima-Nakamura, Akiko, Ito, Emi, Imai, Jun-ichi, Yanagisawa, Yuka, Honma, Reiko, Watanabe, Shinya, Waguri, Satoshi, Ikezoe, Takayuki, Takeishi, Yasuchika
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354500/
https://ncbi.nlm.nih.gov/pubmed/28154173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733030
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