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Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines.

We studied whether a novel vasoconstrictor peptide, endothelin-1 (ET-1), is synthesized by and released from human carcinoma cell lines, and whether ET-1 stimulates proliferation of these tumor cells. ET-1-like immunoreactivity was released from both HeLa and HEp-2 cells as a function of time. Rever...

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Autors principals: Shichiri, M, Hirata, Y, Nakajima, T, Ando, K, Imai, T, Yanagisawa, M, Masaki, T, Marumo, F
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC295314/
https://ncbi.nlm.nih.gov/pubmed/2022753
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