Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines.

We studied whether a novel vasoconstrictor peptide, endothelin-1 (ET-1), is synthesized by and released from human carcinoma cell lines, and whether ET-1 stimulates proliferation of these tumor cells. ET-1-like immunoreactivity was released from both HeLa and HEp-2 cells as a function of time. Rever...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Shichiri, M, Hirata, Y, Nakajima, T, Ando, K, Imai, T, Yanagisawa, M, Masaki, T, Marumo, F
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2022753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115210
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