Paracrine Factors Produced by Bone Marrow Stromal Cells Induce Apoptosis and Neuroendocrine Differentiation in Prostate Cancer Cells

BACKGROUND: Preferential bony metastasis of human prostate cancer (PCa) cells contributes to disease mortality and morbidity. Local factors in bone stromal extracellular matrix microenvironment affect tumor growth through paracrine interactions between tumor and stromal cells. METHODS: Using co-cult...

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Huvudupphovsmän: Zhang, Chu, Soori, Mehrnoosh, Miles, Fayth, Sikes, Robert A., Carson, Daniel D., Chung, Leland L.W., Farach-Carson, Mary C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972389/
https://ncbi.nlm.nih.gov/pubmed/20665531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21231
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