Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?

Fluoropyrimidines, including 5-fluorouracil (5-FU), are widely used in the treatment of solid tumors and remain the backbone of many combination regimens. Despite their clinical benefit, fluoropyrimidines are associated with gastrointestinal and hematologic toxicities, which often lead to treatment...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Del Re, Marzia, Di Paolo, Antonello, van Schaik, Ron H., Bocci, Guido, Simi, Paolo, Falcone, Alfredo, Danesi, Romano
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Netherlands 2010
Gaiak:
Review Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405332/
https://ncbi.nlm.nih.gov/pubmed/23199091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13167-010-0041-2
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak