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TIGAR induces p53-mediated cell-cycle arrest by regulation of RB–E2F1 complex
BACKGROUND: p53 induces cell-cycle arrest and apoptosis in cancer cells and negatively regulates glycolysis via TIGAR. Glycolysis is crucial for cancer progression although TIGAR provides protection from reactive oxygen species and apoptosis. The relation between TIGAR-mediated inhibition of glycoly...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405207/ https://ncbi.nlm.nih.gov/pubmed/22782351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.260 |
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