Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells

BACKGROUND: Sulforaphane (SFN), an isothiocyanate phytochemical present predominantly in cruciferous vegetables such as brussels sprout and broccoli, is considered a promising chemo-preventive agent against cancer. In-vitro exposure to SFN appears to result in the induction of apoptosis and cell-cyc...

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Detalhes bibliográficos
Main Authors: Bryant, Christopher S, Kumar, Sanjeev, Chamala, Sreedhar, Shah, Jay, Pal, Jagannath, Haider, Mahdi, Seward, Shelly, Qazi, Aamer M, Morris, Robert, Semaan, Assaad, Shammas, Masood A, Steffes, Christopher, Potti, Ravindra B, Prasad, Madhu, Weaver, Donald W, Batchu, Ramesh B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838815/
https://ncbi.nlm.nih.gov/pubmed/20196847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-47
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