Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells

BACKGROUND: Sulforaphane (SFN), an isothiocyanate phytochemical present predominantly in cruciferous vegetables such as brussels sprout and broccoli, is considered a promising chemo-preventive agent against cancer. In-vitro exposure to SFN appears to result in the induction of apoptosis and cell-cyc...

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Hlavní autoři: Bryant, Christopher S, Kumar, Sanjeev, Chamala, Sreedhar, Shah, Jay, Pal, Jagannath, Haider, Mahdi, Seward, Shelly, Qazi, Aamer M, Morris, Robert, Semaan, Assaad, Shammas, Masood A, Steffes, Christopher, Potti, Ravindra B, Prasad, Madhu, Weaver, Donald W, Batchu, Ramesh B
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838815/
https://ncbi.nlm.nih.gov/pubmed/20196847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-47
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