Ritonavir-Mediated Induction of Apoptosis in Pancreatic Cancer Occurs via the RB/E2F-1 and AKT Pathways

Recent observations suggest a lower incidence of malignancies in patients infected with HIV during treatment with Highly Active Anti-Retroviral Therapy (HAART) utilizing protease inhibitors. We investigated the effects of ritonavir, a FDA approved HIV protease inhibitor, on proliferation of pancreat...

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Detalhes bibliográficos
Main Authors: Batchu, Ramesh B., Gruzdyn, Oksana V., Bryant, Christopher S., Qazi, Aamer M., Kumar, Sanjeev, Chamala, Sreedhar, Kung, Shu T., Sanka, Ramana S., Puttagunta, Udaya S., Weaver, Donald W., Gruber, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915194/
https://ncbi.nlm.nih.gov/pubmed/24451403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph7010046
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