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Ritonavir-Mediated Induction of Apoptosis in Pancreatic Cancer Occurs via the RB/E2F-1 and AKT Pathways

Recent observations suggest a lower incidence of malignancies in patients infected with HIV during treatment with Highly Active Anti-Retroviral Therapy (HAART) utilizing protease inhibitors. We investigated the effects of ritonavir, a FDA approved HIV protease inhibitor, on proliferation of pancreat...

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Hlavní autoři: Batchu, Ramesh B., Gruzdyn, Oksana V., Bryant, Christopher S., Qazi, Aamer M., Kumar, Sanjeev, Chamala, Sreedhar, Kung, Shu T., Sanka, Ramana S., Puttagunta, Udaya S., Weaver, Donald W., Gruber, Scott A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915194/
https://ncbi.nlm.nih.gov/pubmed/24451403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph7010046
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