TIGAR induces p53-mediated cell-cycle arrest by regulation of RB–E2F1 complex

BACKGROUND: p53 induces cell-cycle arrest and apoptosis in cancer cells and negatively regulates glycolysis via TIGAR. Glycolysis is crucial for cancer progression although TIGAR provides protection from reactive oxygen species and apoptosis. The relation between TIGAR-mediated inhibition of glycoly...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Madan, E, Gogna, R, Kuppusamy, P, Bhatt, M, Pati, U, Mahdi, A A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Molecular Diagnostics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405207/
https://ncbi.nlm.nih.gov/pubmed/22782351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.260
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