Fibroblast EXT1-Levels Influence Tumor Cell Proliferation and Migration in Composite Spheroids

BACKGROUND: Stromal fibroblasts are important determinants of tumor cell behavior. They act to condition the tumor microenvironment, influence tumor growth, support tumor angiogenesis and affect tumor metastasis. Heparan sulfate proteoglycans, present both on tumor and stromal cells, interact with a...

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Hlavní autoři: Österholm, Cecilia, Lu, Ning, Lidén, Åsa, Karlsen, Tine V., Gullberg, Donald, Reed, Rolf K., Kusche-Gullberg, Marion
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405129/
https://ncbi.nlm.nih.gov/pubmed/22848466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041334
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