Fibroblast EXT1-Levels Influence Tumor Cell Proliferation and Migration in Composite Spheroids

BACKGROUND: Stromal fibroblasts are important determinants of tumor cell behavior. They act to condition the tumor microenvironment, influence tumor growth, support tumor angiogenesis and affect tumor metastasis. Heparan sulfate proteoglycans, present both on tumor and stromal cells, interact with a...

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Detalhes bibliográficos
Main Authors: Österholm, Cecilia, Lu, Ning, Lidén, Åsa, Karlsen, Tine V., Gullberg, Donald, Reed, Rolf K., Kusche-Gullberg, Marion
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405129/
https://ncbi.nlm.nih.gov/pubmed/22848466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041334
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