The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups.

Lignende værker

• On the rapid deprotection of synthetic oligonucleotides and analogs.
  af: Polushin, N N, et al.
  Udgivet: (1994)
• Methods of Protection/Deprotection of Hydroxy Groups in the Synthesis of Polyhydroxy Flavonols
  af: Oleksii Demidov, et al.
  Udgivet: (2024-10-01)
• Synthesis of DNA fragments containing 5,6-dihydrothymine, a major product of thymine gamma radiolysis.
  af: Schulhof, J C, et al.
  Udgivet: (1988)
• Advanced method for oligonucleotide deprotection
  af: Surzhikov, Sergey A., et al.
  Udgivet: (2000)
• Reductively-labile sulfonate ester protecting groups that are rapidly cleaved by physiological glutathione
  af: Choi, Adam, et al.
  Udgivet: (2017)