Advanced method for oligonucleotide deprotection

A new procedure for rapid deprotection of synthetic oligodeoxynucleotides has been developed. While all known deprotection methods require purification to remove the residual protective groups (e.g. benzamide) and insoluble silicates, the new procedure based on the use of an ammonia-free reagent mix...

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Autors principals: Surzhikov, Sergey A., Timofeev, Edward N., Chernov, Boris K., Golova, Julia B., Mirzabekov, Andrei D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
Matèries:
NAR Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC102833/
https://ncbi.nlm.nih.gov/pubmed/10734206
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